2016   2015   2014   2013   2012   2011   2010   2009   2008   2007   2005   2004   2003   2002   2001   2000   1999
 

2016

 
Antosova B, Smolikova J, Klimova L, Lachova J, Bendova M, Kozmikova I, Machon O, Kozmik Z
The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6
PLoS Genet. 2016, 12(12):e1006441, doi: 10.1371/journal.pgen.1006441
PubMed PDF

 
Yue JX, Kozmikova I, Ono H, Nossa CW, Kozmik Z, Putnam NH, Yu JK, Holland LZ
Conserved Noncoding Elements in the Most Distant Genera of Cephalochordates: The Goldilocks Principle
Genome Biol Evol. 2016, 8(8):2387-405, doi: 10.1093/gbe/evw158
PubMed PDF

 
Mašek J, Machoň O, Kořínek V, Taketo MM, Kozmik Z
Tcf7l1 protects the anterior neural fold from adopting the neural crest fate
Development. 2016, 143(12):2206-16, doi: 10.1242/dev.132357
PubMed PDF

 
Soukup V, Kozmik Z
Zoology: A New Mouth for Amphioxus
Curr Biol. 2016, 26(9):R367-8, doi: 10.1016/j.cub.2016.03.016
PubMed

 
Fabian P, Pantzartzi CN, Kozmikova I, Kozmik Z
vox homeobox gene: a novel regulator of midbrain-hindbrain boundary development in medaka fish?
Dev Genes Evol. 2016, 226(2):99-107, doi: 10.1007/s00427-016-0533-8
PubMed

 

2015

 
Kozmikova I, Kozmik Z
Gene regulation in amphioxus: An insight from transgenic studies in amphioxus and vertebrates
Mar Genomics. 2015, 24 Pt 2:159-66, doi: 10.1016/j.margen.2015.06.003
PubMed

 
Machon O, Masek J, Machonova O, Krauss S, Kozmik Z.
Meis2 is essential for cranial and cardiac neural crest development
BMC Dev Biol. 2015, 15:40, doi: 10.1186/s12861-015-0093-6
PubMed PDF

 
Liegertová M, Pergner J, Kozmiková I, Fabian P, Pombinho AR, Strnad H, Pačes J, Vlček Č, Bartůněk P, Kozmik Z
Cubozoan genome illuminates functional diversification of opsins and photoreceptor evolution
Sci Rep. 2015, 5:11885, doi: 10.1038/srep11885
PubMed PDF

 
Fabian P, Kozmikova I, Kozmik Z, Pantzartzi CN
Pax2/5/8 and Pax6 alternative splicing events in basal chordates and vertebrates: a focus on paired box domain
Front Genet. 2015, 6:228, doi: 10.3389/fgene.2015.00228
PubMed PDF

 
Klimova L, Antosova B, Kuzelova A, Strnad H, Kozmik Z
Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development
Dev Biol. 2015, 402(1):48-60, doi: 10.1016/j.ydbio.2015.02.023
PubMed PDF

 
Fujimura N, Klimova L, Antosova B, Smolikova J, Machon O, Kozmik Z
Genetic interaction between Pax6 and β-catenin in the developing retinal pigment epithelium
Dev Genes Evol. 2015, 225(2):121-8, doi: 10.1007/s00427-015-0493-4
PubMed

 
Soukup V, Yong LW, Lu TM, Huang SW, Kozmik Z, Yu JK
The Nodal signaling pathway controls left-right asymmetric development in amphioxus
EvoDevo. 2015, 6:5, doi: 10.1186/2041-9139-6-5
PubMed PDF

 

2014

 
Klimova L, Kozmik Z
Stage-dependent requirement of neuroretinal Pax6 for lens and retina development
Development. 2014, 141(6):1292-302, doi: 10.1242/dev.098822
PubMed PDF

 

2013

 
Antosova B, Smolikova J, Borkovcova R, Strnad H, Lachova J, Machon O, Kozmik Z
Ectopic Activation of Wnt/β-Catenin Signaling in Lens Fiber Cells Results in Cataract Formation and Aberrant Fiber Cell Differentiation
PLoS One. 2013, 8(10):e78279, doi: 10.1371/journal.pone.0078279
PubMed PDF

 
Kozmikova I, Candiani S, Fabian P, Gurska D, Kozmik Z
Essential role of Bmp signaling and its positive feedback loop in the early cell fate evolution of chordates
Dev Biol. 2013, 382(2):538-554, doi: 10.1016/j.ydbio.2013.07.021
PubMed PDF

 
Klimova L, Lachova J, Machon O, Sedlacek R, Kozmik Z
Generation of mRx-Cre transgenic mouse line for efficient conditional gene deletion in early retinal progenitors
PLoS One. 2013, 8(5):e63029, doi: 10.1371/journal.pone.0063029
PubMed PDF

 

2012

 
Vopalensky P, Pergner J, Liegertova M, Benito-Gutierrez E, Arendt D, Kozmik Z
Molecular analysis of the amphioxus frontal eye unravels the evolutionary origin of the retina and pigment cells of the vertebrate eye
Proc Natl Acad Sci U S A. 2012, 109(38):15383-8
PubMed PDF

 

2011

 
Kozmikova I, Smolikova J, Vlcek C, Kozmik Z
Conservation and Diversification of an Ancestral Chordate Gene Regulatory Network for Dorsoventral Patterning
PLoS ONE 2011, 6(2):e14650, doi: 10.1371/journal.pone.0014650
PLoS One PDF

 

2010

 
Vopalensky P, Ruzickova J, Pavlu B, Kozmik Z
A lens-specific co-injection marker for medaka transgenesis
Biotechniques 2010, 48(3):235-6, doi: 10.2144/000113368
PubMed PDF

 
Machon O, Kreslova J, Ruzickova J, Vacik T, Klimova L, Fujimura N, Lachova J, Kozmik Z
Lens morphogenesis is dependent on Pax6-mediated inhibition of the canonical Wnt/beta-catenin signaling in the lens surface ectoderm
Genesis 2010, 48(2):86-95, doi: 10.1002/dvg.20583
PubMed

 

2009

 
Vopalensky P and Kozmik Z
Eye evolution: common use and independent recruitment of genetic components
Philos Trans R Soc Lond B Biol Sci. 2009, 364(1531):2819-32, doi: 10.1098/rstb.2009.0079
PubMed PDF

 
Fujimura N, Taketo MM, Mori M, Korinek V, Kozmik Z
Spatial and temporal regulation of Wnt/ß-catenin signaling is essential for development of the retinal pigment epithelium
Dev Biol 2009, 334(1):31-45, doi: 10.1016/j.ydbio.2009.07.002
PubMed PDF

 
Ruzickova J, Piatigorsky J, Kozmik Z
Eye-specific expression of an ancestral jellyfish PaxB gene interferes with Pax6 function despite its conserved Pax6/Pax2 characteristics
Int J Dev Biol. 2009, 53(4):469-82, doi: 10.1387/ijdb.082793jr
PubMed PDF

 

 

2008



 
Kozmik Z, Ruzickova J, Jonasova K, Matsumoto Y, Vopalensky P, Kozmikova I, Strnad H, Kawamura S, Piatigorsky J, Paces V, Vlcek C.
Assembly of the cnidarian camera-type eye from vertebrate-like components.
Proc Natl Acad Sci U S A. 2008, 105(26):8989-93, doi: 10.1073/pnas.0800388105
PubMed PDF

 
Holland LZ, Albalat R, Azumi K, Benito-Gutierrez E, Blow MJ, Bronner-Fraser M, Brunet F, Butts T, Candiani S, Dishaw LJ, Ferrier DE, Garcia-Fernandez J, Gibson-Brown JJ, Gissi C, Godzik A, Hallböök F, Hirose D, Hosomichi K, Ikuta T, Inoko H, Kasahara M, Kasamatsu J, Kawashima T, Kimura A, Kobayashi M, Kozmik Z, Kubokawa K, Laudet V, Litman GW, McHardy AC, Meulemans D, Nonaka M, Olinski RP, Pancer Z, Pennacchio LA, Pestarino M, Rast JP, Rigoutsos I, Robinson-Rechavi M, Roch G, Saiga H, Sasakura Y, Satake M, Satou Y, Schubert M, Sherwood N, Shiina T, Takatori N, Tello J, Vopalensky P, Wada S, Xu A, Ye Y, Yoshida K, Yoshizaki F, Yu JK, Zhang Q, Zmasek CM, Putnam NH, Rokhsar DS, Satoh N, Holland PW
The amphioxus genome illuminates vertebrate origins and cephalochordate biology
Genome Res. 2008, 18(7):1100-11, doi: 10.1101/gr.073676.107
PubMed PDF

 
Jonasova K, Kozmik Z.
Eye evolution: Lens and cornea as an upgrade of animal visual system.
Semin Cell Dev Biol. 2008, 19(2):71-81
PubMed

 
Kozmik Z
The role of Pax genes in eye evolution
Brain Res Bull. 2008; 75(2-4):335-9, doi: 10.1016/j.brainresbull.2007.10.046
PubMed

 
Kozmik Z, Swamynathan SK, Ruzickova J, Jonasova K, Paces V, Vlcek C, Piatigorsky J.
Cubozoan crystallins: evidence for convergent evolution of pax regulatory sequences.
Evol Dev. 2008, 10(1):52-61, doi: 10.1111/j.1525-142X.2007.00213.x
PubMed

 

2007

 
Machon O, Backman M, Machonova O, Kozmik Z, Vacik T, Andersen L, Krauss S.
A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.
Dev Biol. 2007, 311(1):223-37
PubMed

 
Kozmik Z, Holland ND, Kreslova J, Oliveri D, Schubert M, Jonasova K, Holland LZ, Pestarino M, Benes V, Candiani S.
Pax-Six-Eya-Dach network during amphioxus development: Conservation in vitro but context-specificity in vivo.
Dev Biol. 2007, 306(1):143-59
PubMed PDF

 
Kreslova J, Machon O, Ruzickova J, Lachova J, Wawrousek EF, Kemler R, Krauss S, Piatigorsky J, Kozmik Z.
Abnormal lens morphogenesis and ectopic lens formation in the absence of beta-catenin function.
Genesis. 2007, 45(4):157-168
PubMed

 
Fujimura N, Vacik T, Machon O, Vlcek C, Scalabrin S, Speth M, Diep D, Krauss S, Kozmik Z.
Wnt-mediated down-regulation of Sp1 target genes by a transcriptional repressor Sp5.
J Biol Chem. 2007, 282(2):1225-37
PubMed PDF


 

2005

 
Machon O, Backman M, Krauss S, Kozmik Z.
The cellular fate of cortical progenitors is not maintained in neurosphere cultures.
Mol Cell Neurosci. 2005, 30(3):388-97
PubMed

 
Grinchuk O, Kozmik Z, Wu X, Tomarev S.
The Optimedin gene is a downstream target of Pax6.
J Biol Chem. 2005, 280(42):35228-37
PubMed PDF

 
Kozmik Z.
Pax genes in eye development and evolution.
Curr Opin Genet Dev. 2005, 15(4):430-8
PubMed

 
Backman M, Machon O, Mygland L, van den Bout CJ, Zhong W, Taketo MM, Krauss S.
Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon.
Dev Biol. 2005, 279(1):155-68
PubMed PDF

 

2004

 
Diep DB, Hoen N, Backman M, Machon O, Krauss S.
Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain.
Brain Res Dev Brain Res. 2004, 153(2):261-70
PubMed

 
Piatigorsky J. and Kozmik Z.
Cubozoan jellyfish: an Evo/Devo model for eyes and other sensory systems.
Int. J. Dev. Biol. 2004, 48(8-9):719-29
PubMed PDF

 

2003

 
Wu K, Yang Y, Wang C, Davoli MA, D'Amico M, Li A, Cveklova K, Kozmik Z, Lisanti MP, Russell RG, Cvekl A, Pestell RG.
DACH1 inhibits transforming growth factor-beta signaling through binding Smad4.
J Biol Chem. 2003, 278(51):51673-84
PubMed PDF

 
Machon O, van den Bout CJ, Backman M, Kemler R, Krauss S.
Role of beta-catenin in the developing cortical and hippocampal neuroepithelium.
Neuroscience 2003, 122(1):129-43
PubMed

 
Kozmik Z, Daube M, Frei E, Norman B, Kos L, Dishaw LJ, Noll M, Piatigorsky J.
Role of Pax genes in eye evolution: a cnidarian PaxB gene uniting Pax2 and Pax6 functions.
Dev Cell. 2003, 5(5):773-85
PubMed PDF

 
Candiani S, Kreslova J, Benes V, Oliveri D, Castagnola P, Pestarino M, Kozmik Z
Cloning and developmental expression of amphioxus Dachschund.
Gene Expr Patterns 2003, 3(1):65-9
PubMed

 

2002

 
Kralova J, Czerny T, Spanielova H, Ratajova V, Kozmik Z.
Complex regulatory element within the gammaE- and gammaF-crystallin enhancers mediates Pax6 regulation and is required for induction by retinoic acid.
Gene 2002, 286(2):271-82
PubMed

 

2001

 
Kozmik Z, Machon O, Kralova J, Kreslova J, Paces J, Vlcek C.
Characterization of mammalian orthologues of the Drosophila osa gene: cDNA cloning, expression, chromosomal localization, and direct physical interaction with Brahma chromatin-remodeling complex.
Genomics 2001, 73(2):140-8
PubMed

 

2000

 
Piatigorsky J, Kozmik Z, Horwitz J, Ding L, Carosa E, Robison WG Jr, Steinbach PJ, Tamm ER.
Omega crystallin of the scallop lens. A dimeric aldehyde dehydrogenase class 1/2 enzyme-crystallin.
J Biol Chem. 2000, 275(52):41064-73
PubMed PDF

 
Duncan MK, Kozmik Z, Cveklova K, Piatigorsky J, Cvekl A.
Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression.
J Cell Sci. 2000, 113 (Pt 18):3173-85
PubMed PDF

 

1999

 
Kozmik Z, Pfeffer P, Kralova J, Paces J, Paces V, Kalousova A, Cvekl A.
Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene.
Dev Genes Evol. 1999, 209(9):537-45
PubMed

 
Kozmik Z, Holland ND, Kalousova A, Paces J, Schubert M, Holland LZ.
Characterization of an amphioxus paired box gene, AmphiPax2/5/8: developmental expression patterns in optic support cells, nephridium, thyroid-like structures and pharyngeal gill slits, but not in the midbrain-hindbrain boundary region.
Development. 1999, 126(6):1295-304
PubMed PDF